DNA-functionalized colloids: Physical properties and applications

Geerts, Nienke and Eiser, Erika (2010) DNA-functionalized colloids: Physical properties and applications. Soft Matter, 6 (19). pp. 4647-4660. DOI 10.1039/C001603A

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Abstract

The specificity and reversibility of the hydrogen-bonding between two complementary strands in DNA make this bio-molecule a unique binding agent. When DNA is grafted to nano-and micrometer sized colloids it can lead to specific binding between particles coated with complementary strands of single-stranded DNA. DNA-coated colloids hold great promise as the building blocks of a new generation of complex, self-assembling colloidal materials. This brief review sketches the recent developments and present status of the research on DNA-coated colloids with special emphasis on their role as potential building blocks in complex, self-assembling materials and as highly sensitive bio-sensors. Although the present review cannot be comprehensive, it hopefully highlights the promise of DNA-coated colloids as versatile and still largely unexplored form of soft matter.

Item Type: Article
Uncontrolled Keywords: 2010AREP; IA61;
Subjects: 03 - Mineral Sciences
Divisions: 99 - Other
Journal or Publication Title: Soft Matter
Volume: 6
Page Range: pp. 4647-4660
Identification Number: 10.1039/C001603A
Depositing User: Sarah Humbert
Date Deposited: 09 Oct 2010 12:21
Last Modified: 23 Jul 2013 10:00
URI: http://eprints.esc.cam.ac.uk/id/eprint/1946

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